Volume 32, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



The growth of Rio Grande (RG) virus, the only phlebovirus known to occur in the United States, was studied in , its suspected sand fly vector. RG viral titers in infected flies increased more than 10,000-fold within 7 days after intrathoracic inoculation. Experimentally infected female transmitted virus transovarially (vertically) to 54.8% of their F progeny. This is the first virologically confirmed demonstration of transovarial transmission of a phlebovirus by sand flies. It indicates one mechanism by which RG and possibly other phleboviruses may be maintained in nature.


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  • Accepted : 09 Dec 1982

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