Volume 32, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Crossed immunoelectrophoresis was applied to detect the products of the third component of complement (C) activation in plasma of patients suffering from dengue hemorrhagic fever (DHF), using inulin-treated normal human sera as positive control. In DHF, C split products were demonstrated in severely ill patients classified as having Grade III and Grade IV disease. These split products rapidly disappeared during the convalescent phase. The appearance of C activation products in DHF correlated well with signs of shock. This electropherogram of C activation could be used as a parameter reflecting immunologic activity in dengue hemorrhagic fever.


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