1921
Volume 32, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract

In cerebral malaria, the use of currently recommended doses of intravenous quinine may result in subtherapeutic plasma concentrations during the critical first 24 hours of treatment. A loading dose of quinine (20 mg/kg quinine dihydrochloride, equivalent to 16.7 mg/kg base, infused over 4 hours) proved a rapid and safe method of achieving plasma concentrations above the high minimum inhibitory concentrations for prevalent in Eastern Thailand.

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/content/journals/10.4269/ajtmh.1983.32.1
1983-01-01
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1983.32.1
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  • Accepted : 16 Jun 1982

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