Volume 31, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



In Papua New Guinea, and are common causes of acute malaria in children and an uncommon cause. The increasing prevelance of chloroquine-resistant strains of in Papua New Guinea has prompted the search for alternatives to chloroquine as standard presumptive treatment. Sulfadoxine-pyrimethamine, either alone or in combination with a single dose of chloroquine, was compared with chloroquine alone for treatment of acute vivax malaria in children in Madang. Fever resolution was slowest in the group treated with sulfadoxine-pyrimethamine alone, and time to clearance of parasitemia was significantly longer in this group ( < 0.001). Where possible, species identification should be undertaken in acute malaria and cases of treated with chloroquine.


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