Volume 30, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Mesenteric and intestinal vasculature of mice infected with was injected transaortically with a silicone elastomer. The mesenteries and intestines were then cleared and examined with a stereomicroscope. Marked tortuosity and dilatation of mesenteric and intestinal veins were found to be confined to areas of oviposition and were associated with small arteriovenous shunts which were not present in control animals or areas of intestine devoid of eggs. These findings suggest that splanchnic arterial-portal venous shunts add a hyperkinetic component to intrahepatic portal venous obstruction and synergistically result in portal hypertension.


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