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- ISSN: 0002-9637
- E-ISSN: 1476-1645
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- The American Society of Tropical Medicine and Hygiene
- Source: The American Journal of Tropical Medicine and Hygiene, Volume 30, Issue 6, Nov 1981, p. 1342 - 1343
Quinine alone versus Quinine Plus a Pyrimethamine-Sulfadoxine Combination in the Treatment of Plasmodium Faliciparum Cerebral Malaria *
Abstract
Abstract
Fifty-two patients with severe chloroquine resistant Plasmodium falciparum malaria were treated in a randomized double blind study with either quinine and a single dose of pyrimethamine-sulfadoxine (Fansidar) or quinine alone. Although no statistically significant differences were observed, the 25 patients who received both drugs responded faster and had a more favorable outcome (no deaths) when compared to the 27 who received quinine alone (2 deaths).
Copyright © 1981 by The American Society of Tropical Medicine and Hygiene
- 07 Jul 1981