1921
Volume 30, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Abstract

A feature of fascioliasis in mice and rats is incomplete and generally poor resistance to reinfection. The possibility exists that population heterogeneity amongst parasites (in characteristics such as antigenic variability and infectivity) contributes to the incomplete resistance expressed by already infected rodents to challenge infection. Using different exposure regimes, mice and rats were dosed with infective metacercariae of different single snail-derived clones and challenged with the same or different clonal parasites. The results clearly demonstrate that no better resistance to reinfection is seen with parasites of the homologous clone than with heterologous clone challenge. Thus the poor resistance to reinfection seen in fascioliasis cannot be ascribed readily to antigenic or infectivity differences between clonal metacercariae.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1981.30.1039
1981-09-01
2017-11-23
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1981.30.1039
Loading
  • Accepted : 21 Feb 1981

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error