1921
Volume 30, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

Circulating schistosome antigens (CSA) and circulating immune complexes (CIC) were investigated in serum from 420 patients infected with . The radioimmunoprecipitation-polyethylene glycol assay with [I] anti- rabbit antibodies appeared as a sensitive and specific method to quantify CSA. In fact, more than 75% of the patients showed significant levels of CSA. C1q-binding CIC were also detected in 70% of subjects with schistosomiasis. In addition, a close correlation was observed between levels of CSA and CIC. These data suggest that part of the CIC present in human schistosomiasis are formed by schistosome specific antigens.

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/content/journals/10.4269/ajtmh.1981.30.1020
1981-09-01
2017-11-20
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1981.30.1020
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  • Accepted : 15 Nov 1980

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