1921
Volume 29, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

Amphotericin B, a polyene antibiotic effective against eukaryotic cells, can eliminate the trypomastigote form of from blood stored at 4°C. This antitrypanosomal effect can be achieved with a concentration of 3 µg/ml within 48 hours. This concentration of amphotericin B does not produce hemolysis over a period of 3 weeks. Amphotericin B methyl ester and nystatin are not effective. Amphotericin B may be considered as a replacement for crystal violet in blood bank blood to prevent transfusion-induced Chagas' disease.

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/content/journals/10.4269/ajtmh.1980.29.761
1980-09-01
2017-09-23
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1980.29.761
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  • Accepted : 19 Jan 1980

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