Volume 29, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Antibody responses in mice with a primary infection of either or were studied, using antigen preparations from both species. adult worm extracts (Ouchterlony, indirect hemagglutination) detected schistosomiasis in mice by 5–6 weeks, but did not detect fascioliasis through 12 weeks of infection. soluble egg antigen (Ouchterlony, enzyme-linked immunosorbent assay—ELISA) reacted with the sera of mice infected with by 6–7 weeks of infection; only ELISA reacted with the sera of mice infected with (by 3 weeks of infection). The circumoval precipitin test was specific only for mice infected with , being positive by the 9th week of infection. adult worm extract precipitated (Ouchterlony) the sera of mice with schistosomiasis (7 weeks) and fascioliasis (2 weeks).


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