1921
Volume 29, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

Epizootiological observations on in cattle at Kosti, Sudan, showed a significant fall in age-specific prevalence and intensity with age, based on fecal egg count. To test the possibility that this is due to acquired resistance, Kosti cattle and a control group of cattle of similar breed and age from a nonenzootic area were experimentally challenged with 70,000 cercariae. Clinical observations showed very clearly that the Kosti cattle were able to withstand almost completely the effects of the challenge, whereas the controls developed lethal infections. Resistance was further demonstrated by clear differences between the two groups in terms of their body weights, hematological measurements, histopathological and pathophysiological responses, and worm and egg counts. The data suggested that the main basis of the resistance was a suppression of egg production by the worms from the challenge, rather than absolute prevention of their maturation. There was also evidence of a suppression of the fecundity of worms in the naturally infected Kosti cattle.

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/content/journals/10.4269/ajtmh.1980.29.442
1980-05-01
2017-11-23
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1980.29.442
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  • Accepted : 01 Sep 1979

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