1921
Volume 29, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Abstract

We utilized the circumoval precipitin (COP) test, Ouchterlony immunodiffusion, and the enzyme-linked immunosorbent assay (ELISA) for the serodiagnosis of human infection with or , or with both species of schistosome. Only the COP test correctly identified all of those with schistosome infection, although differentiation as to schistosome species was impossible. Circumoval precipitates around eggs from human urine were more numerous and larger than those around eggs obtained from mouse livers. Ouchterlony immunodiffusion with or worm extract failed to diagnose correctly approximately one of every five infected individuals. Mean absorption values of the soluble egg antigen (SEA) used in the ELISA were similar in serum samples from persons infected with either or both species of blood flukes. This suggests that SEA is not species-specific. The ELISA correctly identified, however, 30 of 32 infected individuals, indicating high sensitivity.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1980.29.1254
1980-11-01
2017-11-18
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1980.29.1254
Loading
  • Accepted : 26 Apr 1980

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error