The Application of the Recombinant DNA Technology to Protozoology: Report of a Workshop
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Kinetoplast DNA is the mitochondrial DNA of trypanosomatids. This DNA consists primarily of thousands of small minicircles which are linked together to form a giant network. Replication of this DNA involves release of individual minicircles from the network to form free minicircles. The free minicircles then replicate and the two progeny are reattached to the network. When all minicircles within the network have replicated, the double-sized network divides to form two progeny structures which are each identical to the parent network.


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