1921
The Application of the Recombinant DNA Technology to Protozoology: Report of a Workshop
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

We have studied the mechanism of antigenic variation by using DNA complementary to the messenger RNAs for four variant surface glycoproteins of . Pure complementary DNAs were obtained by cloning as recombinant DNA in . Using these complementary DNAs as hybridization probes, we have analyzed the genes for these variant surface glycoproteins. The results provide new information on the origin and evolution of antigenic variation, and on the mechanism involved in switching from one antigenic type to another.

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/content/journals/10.4269/ajtmh.1980.29.1033
1980-09-01
2017-09-20
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