Volume 28, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Using the Trager-Jensen method, a second malaria species. , a simian counterpart to the human malaria , has been cultivated successfully. The average growth rate every 3–4 days was 5-fold and the average number of merozoites observed was 14. To date, only rhesus monkey red blood cells (RBC) would support the long-term cultivation of this parasite. Short-term observations indicate that RBC from the squirrel monkey () may support growth but human RBC of each of the four major AB-O types failed to support growth of the parasite. Availability of the -rhesus monkey model would allow for a second parasite-host system for the in vitro and in vivo study of the immunologic responses of the falciparum-like parasite in a more natural host.


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