1921
Volume 28, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Abstract

Using the Trager-Jensen method, a second malaria species. , a simian counterpart to the human malaria , has been cultivated successfully. The average growth rate every 3–4 days was 5-fold and the average number of merozoites observed was 14. To date, only rhesus monkey red blood cells (RBC) would support the long-term cultivation of this parasite. Short-term observations indicate that RBC from the squirrel monkey () may support growth but human RBC of each of the four major AB-O types failed to support growth of the parasite. Availability of the -rhesus monkey model would allow for a second parasite-host system for the in vitro and in vivo study of the immunologic responses of the falciparum-like parasite in a more natural host.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1979.28.591
1979-05-01
2017-10-22
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1979.28.591
Loading
  • Accepted : 23 Dec 1978

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error