Volume 28, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



In the 5-year period 1973–1977, 43 patients infected with and 43 patients infected with were treated with Yomesan® (niclos-amide) in the dosages recommended by the Parasitic Disease Drug Service, Center for Disease Control. The first post-treatment stool specimen and 1-week and 3-month specimens were examined in 13 patients with and 19 patients with . One hundred percent (13/13) of those with and 89% (17/19) of those with had negative examinations at 3 months and were considered cured. Two patients with persistent were cured with a second course of drug without changing the dosage or time schedule. Four of these cases had been unresponsive to an initial course of quinacrine hydrochloride. Thus, niclosamide seems to be an effective, relatively nontoxic drug for the initial therapy of these cestode infections.


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