1921
Volume 27, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

A series of lepidines (6-methoxy-4-methyl-8-aminoquinoline derivatives) was studied in a hamster- model. Members of this class were found to have activity many-fold that of the standard, meglumine antimoniate (Glucantime®). One of them, 8-(6-diethylamino-hexylamino)-6-methoxy-4-methylquinoline, designated WR 6026, when given orally was over 700 times as effective as the standard antimonial drug.

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/content/journals/10.4269/ajtmh.1978.27.751
1978-07-01
2017-11-23
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1978.27.751
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  • Accepted : 11 Mar 1978

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