Volume 27, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



We conducted a prospective study of 77 indigenous African adults with acute diarrhea seeking care at the major hospital in Nairobi, Kenya, to determine the major pathogens responsible for this syndrome in adults. Fecal and blood specimens were collected and examined for enteric bacterial pathogens, viruses, and parasites. In 13 (26%) inpatients and 11 (49%) outpatients was found, and heat-labile and heat-stable forms of enterotoxigenic were found in 9 (18%) inpatients and 1 (4%) outpatient. Human reovirus-like agent titers rose significantly in another 3 (6%). Amebic dysentery was not seen although hemagglutination-inhibition tests for invasive were positive in 4 inpatients. An etiologic agent was found in 65% of patients.


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