Volume 27, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Eighty-nine Neotropical bats of five species were inoculated subcutaneously with epizootic or enzootic strains of Venezuelan encephalitis (VE) virus. Viremia was detected in 92.5% of all bats, but no illness attributable to virus infection was observed. Detectable viremias averaged slightly over 4 days in and , and 2.8 days in , and maximal viremia titers in these three species averaged 6.9, 6.6, and 4.6 log SMicLD per ml of blood, respectively. In general developed and maintained detectable levels of both hemagglutination-inhibition (HI) and neutralizing antibody for as long as tested (up to 506 days), although HI antibody to enzootic VE virus strains disappeared in some . The detectable antibody response of was slower and of lower magnitude and shorter duration than that of , although individual which had lost detectable HI and N antibody resisted challenge. Vertical passage of antibody was observed in three offspring. were found to be only slightly less susceptible to VE virus infection than a U.S. subspecies of the cotton rat (). No virus was recovered by mouse inoculation of organ pools of bats killed as early as 2 days and as late as 299 days after the last day of detectable viremia.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error