1921
Volume 27, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

Treatment of mice infected with with a single oral dose of formulated 4-isothiocyano-4′-nitro-diphenylamine (CGP 4540) restored the capacity of the liver of these animals to metabolize certain drugs. Full recovery required 35–40 weeks. Administration of CGP 4540 to non-infected animals produced no significant changes in the activities of some hepatic drug-metabolizing enzymes.

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/content/journals/10.4269/ajtmh.1978.27.1188
1978-11-01
2017-11-20
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1978.27.1188
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  • Accepted : 03 Jun 1978

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