Volume 26, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Three strains of a new Phlebotomus fever group virus were isolated from pack rats () collected in south Texas during 1973–1974; the name Rio Grande was proposed for this virus. The virus is pH 3.0 labile, sensitive to the action of sodium deoxycholate and heat (56°C) labile. The results of a serosurvey indicated that pack rats are probably the principal vertebrate host for Rio Grande virus and that year-round transmission of the virus may occur. Because no isolations of this virus were made from hematophagous insects, the vector, if any, remains undetermined.


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