1921
Volume 26, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

Thirty-six monkeys were immunized with different concentrations and regimens of heat-stable, serum-soluble (S-) antigens of prior to challenge with the homologous parasite via sporozoite inoculation. Fewer deaths and reduced maximum parasitemias occurred in those animals inoculated with 10 to 40 mg of S-antigen compared to nonimmunized monkeys or those receiving only Freund's adjuvant. Protection was incomplete, however, suggesting that antibodies to S-antigens may have a limited role in protection of hosts to malarial infection.

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/content/journals/10.4269/ajtmh.1977.26.373
1977-05-01
2017-11-17
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1977.26.373
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  • Accepted : 09 Oct 1976

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