1921
Volume 25, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

An enzyme-linked immunosorbent assay (ELISA), and radioimmunoassays using antigen bound to plastic tubes or microcrystalline particles, were adapted for the indirect serological measurement of anti-schistosome antibodies. These alkaline phosphatase and I-labeled anti-immunoglobulin techniques were found to be highly quantitative and adaptable. Comparison showed them to be considerably more sensitive than the indirect hemagglutination and indirect fluorescent antibody techniques. Using adult freeze-thaw antigen, anti-schistosome antibodies were detected in sera from patients infected with and . However, results in patients with schistosomiasis haematobium were generally intermediate between those of patients with schistosomiasis mansoni and normal, uninfected controls.

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/content/journals/10.4269/ajtmh.1976.25.824
1976-11-01
2017-11-17
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1976.25.824
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  • Accepted : 27 Mar 1976

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