Volume 25, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Two epizootic strains of Venezuelan encephalitis (VE) virus from Central America and Mexico were transmitted by a colonized epizootic vector mosquito, , at higher rates than were two enzootic strains when the mosquitoes were infected by intrathoracic inoculation or feeding of virus. Differences in transmission rates also occurred with colonized , but were less marked. Following intrathoracic inoculation of or , epizootic strains grew to slightly higher concentrations in the mosquitoes than did enzootic strains. Intestinal thresholds of infection for were slightly lower for epizootic than for enzootic virus strains, but were essentially equal for . Only a small percentage of individual mosquitoes supported growth of epizootic VE virus, and only 1 of 6 tested transmitted virus by bite. Thus, transmission and growth of virus in these mosquitoes distinguished between these epizootic and enzootic strains of VE virus.


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