1921
Volume 25, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

Rabbits infected with develop precipitins to adult worm homogenates, as observed by Ouchterlony double immunodiffusion (ID) and counterelectrophoresis (CEP). When they are successfully trated with a fasciolicidal drug such as rafoxanide at 5, 6, or 11 weeks of infection their precipitins drop dramatically by 2 weeks post-treatment, they are virtually negative by 4 weeks, and have no detectable precipitins by 5 or 6 weeks post-treatment. The results suggest that ID or CEP can be utilized to show chemotherapeutic success in rabbits infected with and warrant further studies as to their possible application in human fascioliasis.

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/content/journals/10.4269/ajtmh.1976.25.307
1976-03-01
2017-09-25
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1976.25.307
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  • Accepted : 13 Sep 1975

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