Volume 24, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Serum samples from ten children with visceral larva migrans were evaluated by analysis of: immunoglobulin concentrations, precipitin reactions against and antigens and blood group substances, and IgM and IgG activity against antigen by radioimmunoassay (RIA). The elevated concentrations of serum IgE and IgG and the positive precipitin reactions which occurred in some cases are an aid in diagnosis but were not consistently present. Serum IgM concentrations were elevated in all cases. IgM or IgG antibodies against antigen were detected in all cases by a solid phase RIA technique. Radioimmunoassay techniques of this type may provide a superior method of diagnosis, particularly if used with serial serum samples which demonstrate changing levels of antibodies.


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