Volume 24, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



The specificity and sensitivity of adult and larval somatic antigens, and perienteric fluid of and were investigated by using intradermal skin tests in guinea pigs. These animals were infected with low doses (0.01, 0.1 or 1.0 egg/g) of these helminths. larval antigen (TL) induced larger reactions in -infected animals than did the other antigens, suggesting a superior sensitivity for this antigen. In addition, perienteric fluid (AP) provoked skin responses in these animals of a magnitude similar to those induced by TL. The reciprocal relationship, i.e., comparable reactivity of AP and TL in -infected animals, was not apparent. In general, larval antigen and AP elicited larger intradermal reactions than other antigens in -infected animals. The results of this study indicated no superiority of adult antigens in differentiating and infections.


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  • Accepted : 31 Aug 1974

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