1921
Volume 24, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

An in vivo screening system is described in which drugs administered to rats or mice and challenged with sporozoites are evaluated for their antimalarial properties (causal prophylaxis, suppression, therapy) by the presence or absence of exoerythrocytic forms and parasitemia. The system is composed of A/J mice, Sprague-Dawley rats, , and . Good correlation has been found between test results and practical application.

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/content/journals/10.4269/ajtmh.1975.24.179
1975-03-01
2017-09-19
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1975.24.179
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  • Accepted : 01 Nov 1974

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