Volume 23, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



A rapid, accurate immunodiagnostic test for trichinosis has been developed. The test employs particle-associated antigens derived from cell-free homogenates of muscle larvae of in the technique of counterelectrophoresis (CE). A supplementary test using agar gel diffusion (AGD) serves to confirm results obtained by CE. Using these two tests, we showed that 4% (8/189) of normal human sera were positive by CE, and 3% (10/334) of normal human sera were positive by AGD. Both of these values are well within the 5% incidence range of human trichinosis in the United States. Moreover, 90% (94/104) of sera which were positive by the bentonite flocculation test were also positive by both the AGD and CE tests. Sera from patients with parasitic infections other than trichinosis were tested for the presence of cross-reacting antibodies. Included in this group were sera from patients with amebiasis, echinococcosis, filariasis, and schistosomiasis. Among these sera some gave false positive tests when first tested by AGD, but few gave false positives when tested further by CE.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...


Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error