1921
Volume 23, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

A strain of isolated in the Republic of Panama in March 1972 was transferred to the Unit on Human Malaria (LPD, NIAID, NIH) in Atlanta, Georgia. Studies in eight non-immune prisoner volunteers demonstrated that infections with this Panama II strain of recrudesced following treatment with chloroquine 1.5 g (base), amodiaquine 1.4 g (base), chlorguanide 1.3 g (base) over 5 days, or quinine 11.34 g (base) over 7 days. Parasitemia increased during therapy with pyrimethamine 150 mg over 3 days. Infections were cured by treatment with quinine for 10 days (16.2 g base) or by combination therapy with sulfadiazine (10 g in 5 days) plus pyrimethamine (150 mg in 3 days).

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/content/journals/10.4269/ajtmh.1974.23.1
1974-01-01
2017-09-24
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1974.23.1
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  • Accepted : 23 Jun 1973

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