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A detailed study of the records prior to 1960 for two hospitals in San Francisco and Fresno, California, disclosed 25 previously unreported cases of hydatid disease, at least 7 of which were autochthonous to California. This brings to 14 the total number of cases known to have been acquired in this State. Two of these patients, operated upon in July 1928 and January 1942, pre-date the previous earliest surgical record for a hydatid infection acquired in California. Also, a substantiated record of a sheep infection with hydatid cysts in Kern County, California in July 1956 is considerably prior to previously published information on infections in sheep in California.