1921
Volume 22, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Autopsy findings of 124 Filipinos and six Bengalis dying of cholera after 1960 were compared with those of patients who died of this disease before 1960. Before 1960 over 50% of patients dying of cholera succumbed of uremia due to poor renal perfusion. After 1960 the frequency of renal lesions (acute tubular necrosis and vacuolar nephropathy) decreased to 5%. This decrease was most probably the result of current therapy, which utilizes massive fluid and electrolyte replacement. No significant change occurred in the frequency of acute bronchopneumonia, interstitial pneumonia, pulmonary congestion and edema, lipid depletion of the adrenals or focal myocarditis. No common anatomic lesion could be found that increased the susceptibility to cholera infection and ensuing disease among these previously healthy patients.

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/content/journals/10.4269/ajtmh.1973.22.215
1973-03-01
2017-09-20
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1973.22.215
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  • Accepted : 18 Aug 1972

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