1921
Volume 21, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Abstract

A simplified in vitro technique was evaluated for reliability and reproducibility in detecting chloroquine-resistant strains of in Central Thailand. In 55 of 57 subjects the parasites were resistant to chloroquine both in vitro and in vivo. Two subjects who were cured with conventional chloroquine administration had parasites which were resistant in vitro. The major technical limitations of the in vitro test were growth failures with high parasite densities and with immature trophozoites. With these limitations the in vitro technique gave a reliable and reproducible qualitative index of chloroquine resistance in falciparum malaria.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1972.21.6
1972-01-01
2017-11-24
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1972.21.6
Loading
  • Accepted : 17 Sep 1971

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error