1921
Volume 20, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Abstract

The Trinidad strain of Venezuelan equine encephalomyelitis virus was propagated successfully in tissue cultures of germ-free, minced pupae. Peak virus titers of 5.0 to 6.0 log plaque-forming units per ml were reached within 3 to 4 days after cultures were infected. Five serial passages caused no detectable changes in either mouse virulence or plaque-size characteristics of the virus. An attenuated virus strain derived from the Trinidad strain did not multiply in these cultures, and neither virus strain grew in tissue cultures of germ-free minced adult mosquitoes.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1971.20.761
1971-09-01
2017-11-18
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1971.20.761
Loading
  • Accepted : 12 Mar 1971

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error