Volume 20, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



An control program on the island of Koh Samui, Thiland, was evaluated in terms of human infection, both clinical and subclinical. Seroconversion rates to dengue were examined monthly in a sample of school children. Crude antibody conversion rates were about 3 per 100 per month before the control program. Because of small sample size, conversion rates after control could not be accurately determined; by this measurement, transmission was not completely interrupted. Clinical cases were classified by clinical course and serological response. A total of 27 dengue and probable dengue cases were seen. Among these were two of dengue shock syndrome and six of hemorrhagic fever. No case had a primary-type antibody response. Disease patterns were similar to those seen in previous years, except that only one case was recorded after the control program. The control program apparently resulted in marked decreases in vector population, in vector infection rates, and in human disease.


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