Volume 20, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Cross neutralization and precipitin tests were performed with coral snake venoms and rabbit antisera against five venoms to determine the most suitable venoms for producing a polyvalent antivenin useful in treating persons bitten by coral snakes. Antisera were produced against species , and venom but not against venom. The latter was the only venom not neutralized by heterologous antisera. venom was neutralized by all antisera. Anti- serum neutralized more heterologous () venom than homologous () venom. The cross reactions suggest that some venom antigens that elicit precipitating and neutralizing antibodies may be distinct. venom produced the most cross-reactive neutralizing antibody, having neutralized five of six venoms. Of the venoms tested, venom would be most suitable for use in the production of a polyvalent coral snake antivenin.


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