1921
Volume 20, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Abstract

Small peripheral-blood lymphocytes from patients partially immune to infections with either the Malayan (Camp.) or Uganda I strain of underwent transformation to large, ameboid, pyroninophilic blasts when cultured in vitro with extracts of gametocytes or trophozoites. Lymphocytes from uninfected persons did not undergo blastoid transformation when exposed to the same extracts. This phenomenon was demonstrable not only during patent parasitemia but also for as long as 2 years after radical cure of the malaria infection. Polyacrylamide-disc electrophoresis of the gametocyte extracts demonstrated protein bands not present in normal hemolysates.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1971.20.195
1971-03-01
2017-11-21
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1971.20.195
Loading
  • Accepted : 08 Sep 1970

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error