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- ISSN: 0002-9637
- E-ISSN: 1476-1645
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†Please address requests for reprints to Dr. M. W. Rytel, Marquette School of Medicine, Milwaukee County General Hospital, Milwaukee, Wisconsin 53226.
- The American Society of Tropical Medicine and Hygiene
- Source: The American Journal of Tropical Medicine and Hygiene, Volume 19, Issue 6, Nov 1970, p. 929 - 931
Induction of an Interferon-Like Inhibitor by Trypanosoma Cruzi Infection in Mice *
Abstract
Abstract
Infection of mice with Trypanosoma cruzi of the Perú strain was associated with the appearance in the circulation of a viral inhibitor that fulfilled most requirements for classification as an interferon. The inhibitor reached its highest titer several days after infection and persisted, although in diminishing amounts, in the circulation until the termination of the experiment. The peak response preceded by several days the marked parasitic multiplication as evidenced by the number of nests of amastigotes in the heart.
Copyright © 1970 by The American Society of Tropical Medicine and Hygiene
- 09 Apr 1970