1921
Volume 19, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

Evaluation of large numbers of potential antimalarial agents requires systems that are simple, reliable, and accurate. We used one such system that employed multiple, dilute, in vitro cultures of to assess effectiveness of drugs. Assessment was made by observation of changes in morphologic maturation of the parasites, incorporation of C-methionine into protein, and lactic acid production. Reliability was demonstrated by reproducible dose-response relations of known antimalarial drugs.

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/content/journals/10.4269/ajtmh.1970.19.905
1970-11-01
2017-09-21
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1970.19.905
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  • Accepted : 10 Jul 1970

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