Volume 19, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



After a malaria-eradication program, no known autochthonous cases of malaria had occurred on Tobago. West Indies, from 1954 to 1966. In 1969, serum collected on filter-paper rectangles from 983 residents of the island was titrated for the presence of malaria antibody by the indirect hemagglutination test, with as antigen. Serum was collected from three groups: 40 persons previously sampled in 1955; 27 persons that were infected with in 1966; and 916 residents of the island selected from the general population. For the 40 persons resampled, antibody prevalence fell from 79% in 1955 to 10% in 1969. Of the 27 persons involved in the quartan-malaria outbreak in 1966, five (18.5%) had detectable antibody. In the sample of the general population, only 1% had demonstrable antibody and, with one exception, the positive reactions were in serum from older persons. These results indicate that hemagglutination antibodies become negligible in a general population within 15 years after eradication of malaria.


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