Volume 19, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



A study of the ecology of Buttonwillow virus during the period 1961–1968 in Kern County, California, indicated that the basic transmission cycle involves as the vector and leporids, primarily , as the vertebrate hosts. Sixty-one strains of virus were isolated from , but no virus was isolated from numerous pools of ticks, fleas, mosquitoes, or other biting flies. Virus also was isolated from the blood of seven and three . Hemagglutination-inhibition antibody to Buttonwillow virus was demonstrated frequently in serum from (35.0%) and (12.7%), but rarely in rodents (0.7%). There was little or no serologic evidence that Buttonwillow virus infects man, domestic fowl and mammals, wild birds, marsupials, bats, carnivores, amphibians, or reptiles. Buttonwillow virus activity was detected from April through November in the San Joaquin Valley. Peak rates of infection in occurred during April and May, coincidental to the occurrence of peak populations of young and susceptible leporids and the initial increase of antibody prevalence in leporids. Diphasic peaks in antibody prevalence were observed for but not for .


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error