1921
Volume 19, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract

A total of 16 injections of normal rhesus-monkey erythrocyte stromata (0.0625 mg N per injection) and hemolysate (0.0212 mg N per injection) were administered to each of three groups of mice, -30 to -1, +1 to +30, and +31 to +60 days after infection by Puerto Rico strain cercariae. Mice were killed on days 61 to 66 after infection, and parasitemia and hepatic pathology were determined. Mice receiving injections of stromata +31 to +60 days after infection were devoid of schistosomes and schistosome eggs, and macro- and microhistology of the liver was normal. All other infected groups were consistent with control infections. The mechanism involved is undefined, but a sudden, overwhelming host response to the schistosome infection is suggested.

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/content/journals/10.4269/ajtmh.1970.19.284
1970-03-01
2017-09-21
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1970.19.284
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  • Accepted : 29 Oct 1969

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