Volume 18, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



A focus of activity of Cache Valley virus was located in the Lake Mermet Conservation Area of southern Illinois as a result of field and laboratory studies conducted during 1964–1967. During each of the 4 years, multiple virus strains were isolated from mosquitoes collected from resting places in the trunks of several trees. A close association apparently existed in this natural habitat between that mosquito and the virus. Although the vertebrate host was not identified, the results of mosquito host-preference study and results of antibody surveys suggest that cattle may be involved in cycles of Cache Valley virus.


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