1921
Volume 18, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Abstract

A total of 45 injections of guinea-pig kidney extract positive for Forssman antigen (0.1 mg nitrogen per injection) was administered to mice 21 days before infection and until 65 days after infection by Puerto Rico strain cercariae. Infected mice were killed on days 70 to 76 after infection, and parasitemia was determined. Pigment content, measured by total-iron determination, noted in pooled liver samples and adult worm pairs, increased significantly (p, <0.001) in mice receiving kidney extracts, as compared with normal and experimental control animals. Infected mice receiving extract showed similar increases in the percentage of nonviable eggs. The injection of extract alone into normal mice produced no apparent effects. The results suggest that guinea-pig kidney extract positive for Forssman antigen alters the metabolism of adults in mice.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1969.18.683
1969-09-01
2017-09-20
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1969.18.683
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error