1921
Volume 18, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Abstract

A strain of Zika virus (P6-740) was isolated from one of 58 pools of 1,277 mosquitoes collected in cities and towns of peninsular Malaya. The mosquitoes in the positive pool were collected from shop houses in Bentong, a small town in West Central Malaya. No strains of Zika virus were isolated from 59 pools of 4,492 collected in suburban and rural areas and in rubber plantations, nor from any of 179 pools of 27,636 mosquitoes of 23 other species collected in rural areas, rain forests, mangrove swamps, and fresh-water swamp forests throughout Malaya. P6-740 was readily identified as a strain of Zika virus by the use of antiserum from monkeys in the standard hemagglutination-inhibition test and the plaque-reduction neutralization test in Vero cell cultures. Specific identification of P6-740 as Zika virus was also made in cross-neutralization tests in mice with hyperimmune mouse serum prepared to itself, Zika, Spondweni, and other group B arboviruses. The latter method, however, was less specific than the plaque-reduction neutralization test for comparison of Zika and Spondweni viruses.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1969.18.411
1969-05-01
2017-11-21
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1969.18.411
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error