1921
Volume 18, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Abstract

Small-bowel biopsy was performed in 20 soldiers acutely ill with falciparum malaria. Histopathologic examination revealed minimum vascular congestion and edema of the lamina propria. Xylose absorption was impaired in eight of 10 patients tested, the abnormal results ranging between 1.25 and 2.80 g per 5 hours after a 25-g dose. In contrast, lactose-tolerance tests were normal (blood-glucose elevation greater than 20 mg per 100 ml) in 11 of 12 patients tested with an oral dose of 1.5 g per kg of body weight. The histopathologic findings and impairment of xylose absorption suggest that there may be decreased splanchnic blood flow in this disease similar to that observed in simian-malaria models.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1969.18.355
1969-05-01
2017-11-20
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1969.18.355
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error