Volume 17, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Serum from East African patients with infection, lesihmaniasis, and normal human donors was analyzed for γ globulin and IgM levels.

The total γ globulin level was found to be higher among healthy African than among healthy American donors. IgM levels were markedly elevated (up to 10 times the normal) in 42 of 45 cases of infection and at all stages of the disease, even when total γ globulin levels were low. In contrast, in all of the seven leishmaniasis cases (except one early infection) IgM levels were normal in the presence of extremely high total globulin levels.

During a period of 1 to 2 months of treatment, the IgM levels dropped only slightly or not at all in infection. Further studies should be made to determine the correlation between this finding and the relapse rate.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error