Volume 16, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



The response of monkeys infected with was followed using the indirect fluorescent-antibody technique.

All animals showed an increase in FA response as a result of the malarial infection. Individual monkeys reacted quite differently to infection; some required repeated periodic drug therapy, whereas in others chronic infection readily occurred without extended treatment. In some monkeys the antibody response reached very high levels (1:1280), whereas in others the peak response was only 1:80. Thus it would be difficult, if not impossible, to determine the length or intensity of previous infection with by the level of FA response obtained.

Through the use of a filter-paper technique to collect daily serum samples, it was possible to determine that the initial increase in FA response was on the 7th to 9th day of patency.


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