Volume 15, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Serological studies were conducted on 29 leptospiral isolates obtained during an epidemiological investigation of an outbreak of human leptospirosis. The isolates were derived from urine of 2 of 6 patients, from 1 of 15 samples of surface water obtained at the locus of infection and from 15 of 106 trapped mammals as follows: 11 of 27 spiny rats (), 2 of 14 spiny pocket mice (), 1 of 3 opossums () and 1 of 3 four-eyed opossums (). No leptospiras were isolated from 49 short-tailed bats (), 6 small-eared bats (), and 4 long-tongued bats ().

On the basis of cross-agglutination and agglutinin adsorption tests, seven different and hitherto unreported serologic types were classified and designated as follows: serotype (hyos group) isolated from man, spiny rat and spiny pocket mouse; serotype (icterohaemorrhagiae group) isolated from man and spiny rat; serotypes (cynopteri group) isolated from spiny rat, spiny pocket mouse and four-eyed opossum; (bataviae group) isolated from spiny rat; serotype , subserotype , isolated from spiny rat and spiny pocket mouse; (hebdomadis group) isolated from spiny rat and surface water; and (possible new group) isolated from opossum. Evidence of mixed infections was obtained in five animals. The bacteriological findings affirmed previous serological indications that Panama is an area of multiple leptospirosis.


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