Volume 15, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Sixteen ground squirrels were infected with Colorado tick fever virus and placed at 4°C. Seven animals hibernated well, and four of these had viremia when removed from the cold 110 to 124 days later. In three animals, viremia persisted for 11, 17, and 47 days after removal from the cold. The total viremic periods were 127, 133, and 160 days. Neutralizing antibody was demonstrated in a larger proportion of the poor hibernators than of the good hibernators. Limited attempts to infect nymphal ticks by feeding them on animals with post-hibernation viremia were unsuccessful.


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